Tricuspid Regurgitation
Definition
Backflow of blood from the right ventricle into the right atrium during systole - may be acute or chronic.
Etiology
- Functional
    
- Pulmonary hypertension (e. g., mitral stenosis etc.)
 - Right ventricular infarction
 - Annular dilatation
 
 - Anatomic (organic)
    
- Rheumatic heart disease
 - Infective endocarditis
 - Tricuspid valve prolapse
 - Ruptured chordae tendineae
 - Papillary muscle dysfunction
 - Carcinoid syndrome
 - Ebstein's anomaly
 - Pacemaker wire
 
 
Signs and Symptoms
- Usually well tolerated
 - Weakness, Fatigue
 - Jugular venous distention
 - Hepatomegaly, Peripheral edema, Ascites
 
Complications
- Severe right-sided failure
 - Renal failure when severe congestion is present
 
Cardiac Auscultation
- A holosystolic. high-pitched blowing sound heard best in the tricuspid area along the left sternal border over the right ventricular apex
 - The murmur of tricuspid regurgitation may be accentuated with inspiration; this is known as Rivero-Carvallo's sign
 - Right-sided S3 which may be accentuated with inspiration
 
Electrocardiogram
- Right atrial enlargement
 - Incomplete right bundle branch block
 - Atrial fibrillation
 
Chest X-ray
- Right atrial enlargement
 - Right ventricular enlargement
 
Treatment
- None (tricuspid regurgitation may be well tolerated for years)
 - Annuloplasty (Carpentier ring, Kay ring, Duran ring)
 - Tricuspid valve replacement (usually with a tissue valve to reduce the risk of thrombus formation)
 
M-Mode
- Right ventricular-volume overload pattern (right ventricular enlargement with paradoxical septal motion)
 - B "bump" or "notch'' indicates increased right ventricular end diastolic pressure (≥ 9 mm Hg)
 
2-D
- Right atrial enlargement
 - Right ventricular enlargement
 - Right ventricular volume overload pattern (right ventricular enlargement with paradoxical septal motion)
 - Dilated tricuspid valve annulus (> 3. 4 cm) indicates severe tricuspid regurgitation
 - Dilated inferior vena cava (normal: 1. 2 to 2. 3 cm)
 - Dilated hepatic veins (normal: 0. 5 to 1. 1 cm)
 - Persistent contrast echo indicates significant tricuspid regurgitation
 - Systolic reflux of contrast into the inferior vena cava and hepatic veins may also indicate significant tricuspid regurgitation (may also be visualized by color flow Doppler)
 
PW Doppler
- Up to 93% of normal patients appear to have tricuspid regurgitation; calculate the duration and length of the regurgitant jet to differentiate between true and physiologic tricuspid regurgitation
 - Determine tricuspid regurgitation by using the mapping technique
 - Systolic flow reversal in the hepatic veins indicates severe tricuspid regurgitation (may also be detected by color flow Doppler)
 - Laminar tricuspid regurgitation flow may denote significant tricuspid regurgitation
 
CW Doppler
- Compare the regurgitant Doppler spectral display with the tricuspid inflow Doppler spectral display
 - Determine systolic pulmonary artery pressure by the tricuspid regurgitation method.
 
Color Flow Doppler
- Determine regurgitant jet area/right atrial area (see table), using the formula for mitral regurgitation
 - Proximal acceleration (flow convergence) may indicate 3+ or 4+ regurgitation.
 - Systolic flow reversal in the hepatic veins indicates severe tricuspid regurgitation.